ANTIMUTAGENICITY IN EUGLENA-GRACILIS

被引：20

作者：

FOLTINOVA, P

LAHITOVA, N

EBRINGER, L

机构：

[1] Institute of Molecular and Subcellular Biology, Comenius University, 811 07 Bratislava, Odborárske nám

来源：

MUTATION RESEARCH | 1994年 / 323卷 / 04期

关键词：

ANTIMUTAGENICITY; NITROSOGUANIDINE; FURADANTINE; EUGLENA-GRACILIS; SALMONELLA-TYPHIMURIUM;

D O I：

10.1016/0165-7992(94)90029-9

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The genotoxic effect of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and furadantine (Fu) was significantly decreased by standard antimutagens (ascorbic acid, alpha-tocopherol, chlorophyllin and sodium selenite) in the unicellular flagellate Euglena gracilis. The effects of these compounds were verified also by a bacterial test in which three strains of Salmonella typhimurium, TA97, TA100 and TA102, were used. The above compounds were antimutagenic in strains of bacteria used, except for chlorophyllin which had no effect on strain TA102.

引用

页码：167 / 171

页数：5

共 16 条

[1] METHODS FOR DETECTING CARCINOGENS AND MUTAGENS WITH SALMONELLA-MAMMALIAN-MICROSOME MUTAGENICITY TEST [J].