Transcription of ncDNA Many roads lead to local gene regulation

被引:5
作者
Hainer, Sarah I. [1 ]
Martens, Joseph A. [1 ]
机构
[1] Univ Pittsburgh, Dept Biol Sci, Pittsburgh, PA 15260 USA
来源
TRANSCRIPTION-AUSTIN | 2011年 / 2卷 / 03期
关键词
ncDNA transcription; ncRNA; nucleosome; chromatin; histone modifications; transcription interference;
D O I
10.4161/trns.2.3.15684
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Transcription of ncDNA occurs throughout eulcaryotic genomes, generating a wide array of ncRNAs. One large class of ncRNAs includes those transcribed over the promoter regions of nearby protein coding genes. Recent studies, primarily focusing on individual genes have uncovered multiple mechanisms by which promoter-associated transcriptional activity locally alters gene expression.
引用
收藏
页码:120 / 123
页数:4
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