A GENETIC-LINKAGE MAP OF THE BOVINE GENOME

被引：474

作者：

BARENDSE, W

ARMITAGE, SM

KOSSAREK, LM

SHALOM, A

KIRKPATRICK, BW

RYAN, AM

CLAYTON, D

LI, L

NEIBERGS, HL

ZHANG, N

GROSSE, WM

WEISS, J

CREIGHTON, P

MCCARTHY, F

RON, M

TEALE, AJ

FRIES, R

MCGRAW, RA

MOORE, SS

GEORGES, M

SOLLER, M

WOMACK, JE

HETZEL, DJS

机构：

[1] UNIV GEORGIA, DEPT PHYSIOL & PHARMACOL, ATHENS, GA 30602 USA

[2] HEBREW UNIV JERUSALEM, DEPT GENET, IL-91904 JERUSALEM, ISRAEL

[3] UNIV WISCONSIN, DEPT MEAT & ANIM SCI, MADISON, WI 53706 USA

[4] TEXAS A&M UNIV, DEPT VET PATHOBIOL, COLL STN, TX 77843 USA

[5] TEXAS A&M UNIV, CTR ANIM GENET, COLL STN, TX 77843 USA

[6] TRINITY COLL DUBLIN, DEPT GENET, DUBLIN, IRELAND

[7] AGR RES ORG, ANIM GENET & BREEDING UNIT, IL-50250 BET DAGAN, ISRAEL

[8] INT LAB RES ANIM DIS, NAIROBI, KENYA

[9] ETH ZUERICH, INST NUTZTIERWISSENSCH, CH-8092 ZURICH, SWITZERLAND

[10] GENMARK INC, SALT LAKE CITY, UT 84108 USA

来源：

NATURE GENETICS | 1994年 / 6卷 / 03期

关键词：

D O I：

10.1038/ng0394-227

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A cattle genetic linkage map was constructed which marks about 90% of the expected length of the cattle genome. Over 200 DNA polymorphisms were genotyped in cattle families which comprise 295 individuals in full sibling pedigrees. One hundred and seventy-one loci were found linked to one-other locus. Twenty nine of the 30 chromosome pairs are represented by at least one of the 36 linkage groups. Less than a 50 cM difference was found in the male and female genetic maps. The conserved loci on this map show as many differences in gene order compared to humans as is found between humans and mice. The conservation is consistent with the patterns of karyotypic evolution found in the rodents, primates and artiodactyls. This map will be important for localizing quantitative trait loci and provides a basis for further mapping.

引用

页码：227 / 235

页数：9

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