METABOLITES OF STREPTOMYCES NOURSEI .X. BIOGENESIS OF CYCLOHEXIMIDE

被引：6

作者：

VANEK, Z

PUZA, M

CUDLIN, J

VONDRACEK, M

RICKARDS, RW

机构：

[1] Department of Biogenesis of Natural Substances, Institute of Microbiology, Czechoslovak Academy of Sciences

[2] Research Institute of Antibiotics and Biotransformations, Roztoky near Prague

[3] Research School of Chemistry, The Australian National University, Canberra

来源：

FOLIA MICROBIOLOGICA | 1969年 / 14卷 / 04期

关键词：

D O I：

10.1007/BF02872708

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The antibiotic cycloheximide is formed biogenetically from six malonate units, five of which undergo decarboxylation, both methyl groups are of methionine origin. The biogenesis of the glutarimide part of the molecule is nonstereospecific. Degradation procedures using14C-labelled substrates are described. © 1969 Institute of Microbiology, Academy of Sciences of the Czech Republic.

引用

页码：388 / +

页数：1

共 16 条

[1] STUDIES IN RELATION TO BIOSYNTHESIS .13. GRISEOFULVIN
BIRCH, AJ
MASSYWESTROPP, RA
RICKARDS, RW
SMITH, H
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1958, (JAN): : 360 - 365
[2] METABOLITES OF STREPTOMYCES NOURSEI .8. BIOGENESIS OF CYCLOHEXIMIDE FROM POINT OF VIEW OF GLUTARIMIDE RING SYMETRY
CUDLIN, J
PUZA, M
VONDRACEK, M
VANEK, Z
RICKARDS, RW
[J]. FOLIA MICROBIOLOGICA, 1967, 12 (04) : 376 - +
[3] ON THE ABSOLUTE CONFIGURATION OF THE ANTIBIOTIC ACTIDIONE
EISENBRAUN, EJ
OSIECKI, J
DJERASSI, C
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1958, 80 (05) : 1261 - 1262
[4] TOTAL SYNTHESIS OF CYCLOHEXIMIDE
JOHNSON, F
STARKOVSKY, NA
PATON, AC
CARLSON, AA
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1966, 88 (01) : 149 - +
[5] GLUTARIMIDE ANTIBIOTICS .7. SYNTHESIS OF DL-NEOCYCLOHEXIMIDE AND DETERMINATION OF CYCLOHEXANONE RING STEREOCHEMISTRY OF CYCLOHEXIMIDE ITS ISOMERS AND INACTONE
JOHNSON, F
STARKOVS.NA
GUROWITZ, DW
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1965, 87 (15) : 3492 - &
[6] KHARATYAN S, 1963, CHEM IND-LONDON, P1038
[7] THE STRUCTURE AND CHEMISTRY OF ACTIDIONE, AN ANTIBIOTIC FROM STREPTOMYCES GRISEUS
KORNFELD, EC
JONES, RG
PARKE, TV
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1949, 71 (01) : 150 - 159
[8] PUZA M, 1966, ANTIBIOTICS ADVANCES, P582
[9] SAKAMI W, 1955, HANDBOOK ISOTOPE TRA, P63
[10] SAKAMI W, 1955, HANDBOOK ISOTOPE ED, P52

← 1 2 →