METABOLITES OF STREPTOMYCES NOURSEI .X. BIOGENESIS OF CYCLOHEXIMIDE

被引：6

作者：

VANEK, Z

PUZA, M

CUDLIN, J

VONDRACEK, M

RICKARDS, RW

机构：

[1] Department of Biogenesis of Natural Substances, Institute of Microbiology, Czechoslovak Academy of Sciences

[2] Research Institute of Antibiotics and Biotransformations, Roztoky near Prague

[3] Research School of Chemistry, The Australian National University, Canberra

来源：

FOLIA MICROBIOLOGICA | 1969年 / 14卷 / 04期

关键词：

D O I：

10.1007/BF02872708

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The antibiotic cycloheximide is formed biogenetically from six malonate units, five of which undergo decarboxylation, both methyl groups are of methionine origin. The biogenesis of the glutarimide part of the molecule is nonstereospecific. Degradation procedures using14C-labelled substrates are described. © 1969 Institute of Microbiology, Academy of Sciences of the Czech Republic.

引用

页码：388 / +

页数：1

共 16 条

[11] STARKOVSKY NA, 1964, TETRAHEDRON LETT, P919
[12] METABOLITES OF STREPTOMYCES NOURSEI .3. INCORPORATION OF 14C-CARBON DIOXIDE INTO CYCLOHEXIMIDE
VANEK, Z
DOLEZILOVA, L
PUZA, M
CUDLIN, J
VONDRACEK, M
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1964, 17 (05) : 532 - &
[13] VANEK Z., 1966, Biogenesis of cycloheximide and of related compounds., P982
[14] VANEK Z, 1967, ANTIBIOTICS, V2, P222
[15] VONDRACEK M, 1964, CHEM IND-LONDON, P1686
[16] Wallach O, 1913, LIEBIGS ANN CHEM, V395, P74

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