MONOCYTE ANTIMYCOBACTERIAL ACTIVITY BEFORE AND AFTER MYCOBACTERIUM-BOVIS BCG VACCINATION IN CHINGLEPUT, INDIA, AND LONDON, UNITED-KINGDOM

被引:22
作者
CHENG, SH
WALKER, KB
LOWRIE, DB
MITCHISON, DA
SWAMY, R
DATTA, M
PRABHAKAR, R
机构
[1] NATL INST MED RES,LEPROSY & MYCOBACTERIA LAB,RIDGEWAY,MILL HILL,LONDON NW7 1AA,ENGLAND
[2] ROYAL POSTGRAD MED SCH,DEPT BACTERIOL,LONDON W12 0HS,ENGLAND
[3] TB RES CTR,MADRAS 600031,INDIA
关键词
D O I
10.1128/IAI.61.10.4501-4503.1993
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Monocytes from purified protein derivative S Mantoux-negative children and young adults inhibited intracellular growth of Mycobacterium microti more in Chingleput than in London. Mycobacterium bovis BCG vaccination did not enhance bacteriostasis with the Indians but did so with the Londoners. No evidence was found for involvement of cytokines such as macrophage-activating factor and granulocyte macrophage colony-stimulating factor in the differences.
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页码:4501 / 4503
页数:3
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