PREPARATIVE SEPARATION OF ENANTIOMERS USING HOLLOW-FIBER MEMBRANE TECHNOLOGY

被引：53

作者：

PIRKLE, WH

BOWEN, WE

机构：

[1] School of Chemical Sciences, University of Illinois, Urbana

来源：

TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 05期

关键词：

D O I：

10.1016/S0957-4166(00)86224-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Several chromatographically developed chiral selectors show promise for large scale separation of enantiomers using hollow-fiber membrane technology. Chiral selectors derived from N(1-naphthyl)leucine have been used in a hollow-fiber membrane system (Sepracor) to separate the enantiomers of amino acid derivatives. Enantiomeric purities exceeding 95% have been obtained in a single pass through the system For data collection, sample sizes were limited to gram quantities of racemate.

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页码：773 / 776

页数：4

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