ENHANCED REACTION-RATE AND ENANTIOSELECTIVITY IN LIPASE-CATALYZED HYDROLYSIS BY ADDITION OF A CROWN-ETHER

被引：35

作者：

ITOH, T ^{[1
]}

HIYAMA, Y ^{[1
]}

BETCHAKU, A ^{[1
]}

TSUKUBE, H ^{[1
]}

机构：

[1] OKAYAMA UNIV,COLL LIBERAL ARTS & SCI,DEPT CHEM,OKAYAMA 700,JAPAN

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 16期

关键词：

D O I：

10.1016/S0040-4039(00)77639-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Both reaction rate and enantioselectivity in a lipase-catalyzed hydrolysis of beta-acetoxybutyronitrile were significantly enhanced by addition of hydroxymethyl-12-crown-4.

引用

页码：2617 / 2620

页数：4

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