HIGHLY DIASTEREOSELECTIVE BIS-HYDROXYLATION OF THE AMINO-DEOXY-CONDURITOL-C RING-SYSTEM - A FORMAL SYNTHESIS OF THE AMINOCYCLITOL MOIETY OF THE ANTIBIOTIC HYGROMYCIN-A

被引：28

作者：

ARJONA, O

DEDIOS, A

PLUMET, J

SAEZ, B

机构：

[1] Departamento de Química Orgánica I, Facultad de Química, Universidad Complutense

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 08期

关键词：

D O I：

10.1016/0040-4039(94)02465-N

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A formal synthesis of the aminocyclitol fragment of the antibiotic Hygromycin A is reported using, as a key step, a highly diastereoselective bis-hydroxylation of an amino-deoxy-conduritol C derivative, easily accesible from an 7-oxanorbornenic derivative which in turn can be synthesised from furan.

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页码：1319 / 1320

页数：2

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