STEREOSELECTIVE SYNTHESIS OF CYCLIC DINUCLEOTIDE PHOSPHOROTHIOATES

被引：20

作者：

BATTISTINI, C

FUSTINONI, S

BRASCA, MG

BORGHI, D

机构：

[1] Farmitalia Carlo Erba - Research and Development, 20014 Nerviano, MI, Via Giovanni XXIII

来源：

TETRAHEDRON | 1993年 / 49卷 / 05期

关键词：

CYCLIC OLIGONUCLEOTIDES; PHOSPHOROTHIOATES; HYDROGEN PHOSPHONATE; STEREOSELECTIVE CYCLIZATION; CYTIDINE DINUCLEOTIDE;

D O I：

10.1016/S0040-4020(01)86292-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cyclic dicytidyl phosphorothioates have been synthesized by using the hydrogenphosphonate methodology followed by oxidative sulfurization with a complete stereoselectivity in the cyclization step.

引用

页码：1115 / 1132

页数：18

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