ONLINE DETECTION OF BASE-LINE VARIATIONS THROUGH TORQUE MEASUREMENTS IN ISOTHERMAL REACTION CALORIMETERS

In addition to on-line detection of events in biotechnology, calorimetry could be used to control processes. In the latter case, a correct and instantaneous heat signal must be available. This would only be possible if a correct evaluation of baseline evolution was possible. In this paper it is shown that torque measurements are a powerful tool for detecting and correcting baseline 'shifts and for eliminating external perturbations during cultures of a filamentous bacterium.