ASYMMETRIC-SYNTHESIS OF D- AND L-2-DEOXY-4-THIORIBOSES

被引：37

作者：

UENISHI, J

MOTOYAMA, M

TAKAHASHI, K

机构：

[1] Department of Chemistry, Faculty of Science Okayama University of Science Ridaicho, Okayama

来源：

TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 01期

关键词：

D O I：

10.1016/S0957-4166(00)80489-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Both D- and L-enantiomers of 2-deoxy-4-thioribose derivatives 12 and 17 were prepared stereospecifically in 12 steps from 1,3-propanediol. The key intermediary 2,3-epoxy alcohols, 8 and 15 were obtained with high enantiomeric excess by the Sharpless asymmetric epoxidation using (+)-L-diethyl tartrate and (-)-D-diethyl tartrate.

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页码：101 / 110

页数：10

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