SYNTHESIS OF NOVEL PHOSPHORAMIDITE DERIVATIVES BEARING PYRENYL AND DANSYL GROUPS

被引:7
作者
BURMEISTER, J [1 ]
AZZAWI, A [1 ]
VONKIEDROWSKI, G [1 ]
机构
[1] UNIV FREIBURG,INST ORGAN CHEM & BIOCHEM,D-79104 FREIBURG,GERMANY
关键词
D O I
10.1016/0040-4039(95)00598-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of novel phosphoramidites is reported starting with the readily available 4-(1-pyrenyl)-butanol or 5-(dimethylamino)naphthalene-1-sulfonic acid chloride, respectively. Both amidites can be used on the DNA synthesizer to prepare 5'- or internally labeled oligonucleotides without an acyl amide linkage to the fluorescent dye.
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页码:3667 / 3668
页数:2
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