REACTIONS OF 1-SUBSTITUTED-POLYFLUORO-1-PROPENYL P-TOLUENESULFONATES WITH BIFUNCTIONAL NITROGEN NUCLEOPHILES - A NEW EXPEDIENT ACCESS TO MONOFLUORINATED NITROGEN-HETEROCYCLES

被引：25

作者：

FUNABIKI, K

OHTSUKI, T

ISHIHARA, T

YAMANAKA, H

机构：

来源：

CHEMISTRY LETTERS | 1995年 / 03期

关键词：

D O I：

10.1246/cl.1995.239

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1-Substituted-2,3,3-trifluoro-1-propenyl p-toluenesulfonates, readily available by the alkylation or arylation of 2,3,3-trifluoro-1-tosyloxy-1-propenyllithium or -zinc reagent, reacted smoothly with amidine or hydrazine derivatives at 70 degrees C for 1 h to give the corresponding 5-fluoropyrimidine or 4-fluoropyrazole compounds, respectively, in moderate to excellent yields.

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页码：239 / 240

页数：2

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