BIOLOGICAL RESPONSE TO CHOPPED-CARBON-FIBER-REINFORCED PEEK

被引:128
作者
JOCKISCH, KA
BROWN, SA
BAUER, TW
MERRITT, K
机构
[1] CASE WESTERN RESERVE UNIV,DEPT BIOMED ENGN,CLEVELAND,OH 44106
[2] CLEVELAND CLIN EDUC FDN,DEPT PATHOL,CLEVELAND,OH 44106
来源
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH | 1992年 / 26卷 / 02期
关键词
D O I
10.1002/jbm.820260202
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Polymer composites are being recognized as important implant materials for fracture fixation plates. The use of a composite material is dependent upon the mechanical properties of the material and its biocompatibility. The primary objective of this project was to evaluate 30% chopped-carbon-fiber-reinforced poly(etheretherketone) (CFRPEEK) as a potential material for use as a fracture fixation plate. A two-phase study was conducted. The first phase analyzed the short-term biocompatibility of CFRPEEK through rabbit muscle implant testing. CFRPEEK exhibited a nonspecific foreign body tissue reaction similar to the response observed with ultra-high-molecular-weight polyethylene (UHMWPE). In the second phase, four-hole CFRPEEK plates were implanted as internal fixation devices for transverse midshaft femoral osteotomies in beagles. The plates were effective in promoting fracture healing. A nonspecific foreign body reaction was observed to the plates and to particulate debris.
引用
收藏
页码:133 / 146
页数:14
相关论文
共 16 条
  • [11] THE EFFECTS OF METAL PLATES ON POST-TRAUMATIC REMODELING AND BONE MASS
    UHTHOFF, HK
    FINNEGAN, M
    [J]. JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 1983, 65 (01): : 66 - 71
  • [12] UHTHOFF HK, 1971, CLIN ORTHOP RELAT R, V81, P165
  • [13] INVITRO BIOCOMPATIBILITY OF POLYETHERETHERKETONE AND POLYSULFONE COMPOSITES
    WENZ, LM
    MERRITT, K
    BROWN, SA
    MOET, A
    STEFFEE, AD
    [J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1990, 24 (02): : 207 - 215
  • [14] POTENTIAL OF POLYETHERETHERKETONE (PEEK) AND CARBON-FIBER-REINFORCED PEEK IN MEDICAL APPLICATIONS
    WILLIAMS, DF
    MCNAMARA, A
    TURNER, RM
    [J]. JOURNAL OF MATERIALS SCIENCE LETTERS, 1987, 6 (02) : 188 - 190
  • [15] Woo S L, 1984, J Orthop Res, V1, P431
  • [16] ZIMMERMAN M, 1987, J BIOMED MATER RES-A, V21, P345