ANTIGEN-SPECIFICITY OF GAMMA-DELTA LYMPHOCYTES-T

被引：55

作者：

BORN, WK

OBRIEN, RL

MODLIN, RL

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT MICROBIOL & IMMUNOL,LOS ANGELES,CA 90024

[2] UNIV COLORADO,HLTH SCI CTR,DEPT MICROBIOL & IMMUNOL,DENVER,CO 80262

[3] UNIV CALIF LOS ANGELES,SCH MED,DIV DERMATOL,LOS ANGELES,CA 90024

来源：

FASEB JOURNAL | 1991年 / 5卷 / 12期

关键词：

GAMMA-DELTA T-CELLS; INFECTION; SPECIFICITY; FUNCTION;

D O I：

10.1096/fasebj.5.12.1717333

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Gamma-delta-T cells represent a new lymphocyte subset without a definitive functional assignment. Although in many ways similar to alpha-beta-T lymphocytes, they are clearly distinguished by their expression of a different set of T cell receptor genes, a different distribution in normal tissues, and perhaps also different ligand specificities. Because gamma-delta-T cells appear to be involved in a variety of human diseases, the determination of their biological role has become an important challenge for immunologists and researchers in related areas.

引用

页码：2699 / 2705

页数：7