ANTIGEN-SPECIFICITY OF GAMMA-DELTA LYMPHOCYTES-T

被引：55

作者：

BORN, WK

OBRIEN, RL

MODLIN, RL

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT MICROBIOL & IMMUNOL,LOS ANGELES,CA 90024

[2] UNIV COLORADO,HLTH SCI CTR,DEPT MICROBIOL & IMMUNOL,DENVER,CO 80262

[3] UNIV CALIF LOS ANGELES,SCH MED,DIV DERMATOL,LOS ANGELES,CA 90024

来源：

FASEB JOURNAL | 1991年 / 5卷 / 12期

关键词：

GAMMA-DELTA T-CELLS; INFECTION; SPECIFICITY; FUNCTION;

D O I：

10.1096/fasebj.5.12.1717333

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Gamma-delta-T cells represent a new lymphocyte subset without a definitive functional assignment. Although in many ways similar to alpha-beta-T lymphocytes, they are clearly distinguished by their expression of a different set of T cell receptor genes, a different distribution in normal tissues, and perhaps also different ligand specificities. Because gamma-delta-T cells appear to be involved in a variety of human diseases, the determination of their biological role has become an important challenge for immunologists and researchers in related areas.

引用

页码：2699 / 2705

页数：7

共 92 条

[41] RECOGNITION OF THE PRODUCT OF A NOVEL MHC TL REGION GENE (27B) BY A MOUSE GAMMA-DELTA-T-CELL RECEPTOR
ITO, K
VANKAER, L
BONNEVILLE, M
HSU, S
MURPHY, DB
TONEGAWA, S
[J]. CELL, 1990, 62 (03) : 549 - 561
[42] DIFFERENT GAMMA-DELTA-T-CELL RECEPTORS ARE EXPRESSED ON THYMOCYTES AT DIFFERENT STAGES OF DEVELOPMENT
ITO, K
BONNEVILLE, M
TAKAGAKI, Y
NAKANISHI, N
KANAGAWA, O
KRECKO, EG
TONEGAWA, S
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (02) : 631 - 635
[43] HOMING OF A GAMMA-DELTA THYMOCYTE SUBSET WITH HOMOGENEOUS T-CELL RECEPTORS TO MUCOSAL EPITHELIA
ITOHARA, S
FARR, AG
LAFAILLE, JJ
BONNEVILLE, M
TAKAGAKI, Y
HAAS, W
TONEGAWA, S
[J]. NATURE, 1990, 343 (6260) : 754 - 757
[44] SPECIFICITY AND FUNCTION OF T-CELLS BEARING GAMMA-DELTA-RECEPTORS
JANEWAY, CA
JONES, B
HAYDAY, A
[J]. IMMUNOLOGY TODAY, 1988, 9 (03): : 73 - 76
[45] ACTIVATION OF GAMMA-DELTA-T-CELLS IN THE PRIMARY IMMUNE-RESPONSE TO MYCOBACTERIUM-TUBERCULOSIS
JANIS, EM
KAUFMANN, SHE
SCHWARTZ, RH
PARDOLL, DM
[J]. SCIENCE, 1989, 244 (4905) : 713 - 716
[46] TRANSCRIPTS OF FUNCTIONALLY REARRANGED GAMMA GENES IN PRIMARY T-CELLS OF ADULT IMMUNOCOMPETENT MICE
JONES, B
MJOLSNESS, S
JANEWAY, C
HAYDAY, AC
[J]. NATURE, 1986, 323 (6089) : 635 - 638
[47] MOLECULAR ANALYSIS OF T-CELL RECEPTOR GAMMA-GENE EXPRESSION IN ALLO-ACTIVATED SPLENIC T-CELLS OF ADULT MICE
JONES, B
CARDING, S
KYES, S
MJOLSNESS, S
JANEWAY, C
HAYDAY, A
[J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 1988, 18 (12) : 1907 - 1915
[48] GAMMA-DELTA T-CELL RECEPTOR POSITIVE T-CELL CLONES DERIVED FROM HUMAN HEART-TRANSPLANTS DO NOT SHOW DONOR-SPECIFIC CYTOTOXICITY
JUTTE, NHPM
VANDEKERCKHOVE, BAE
VAESSEN, LMB
OUWEHAND, AJ
BAAN, CC
BOS, E
CLAAS, FHJ
WEIMAR, W
[J]. HUMAN IMMUNOLOGY, 1990, 28 (02) : 170 - 174
[49] A LARGE FRACTION OF HUMAN PERIPHERAL-BLOOD -GAMMA-DELTA+ T-CELLS IS ACTIVATED BY MYCOBACTERIUM-TUBERCULOSIS BUT NOT BY ITS 65-KD HEAT-SHOCK PROTEIN
KABELITZ, D
BENDER, A
SCHONDELMAIER, S
SCHOEL, B
KAUFMANN, SHE
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1990, 171 (03) : 667 - 679
[50] KAUFMANN SHE, IN PRESS CURR TOP MI

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