DETERMINATION OF ISOFLAVONES USING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH ATMOSPHERIC-PRESSURE CHEMICAL-IONIZATION MASS-SPECTROMETRY

被引：20

作者：

ARAMENDIA, MA

GARCIA, I

LAFONT, F

MARINAS, JM

机构：

[1] Department of Organic Chemistry and Mass Spectrometry, Faculty of Sciences, University of Córdoba, Cordoba, E-14004, Avda S. Alberto Magno s/n

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1995年 / 9卷 / 06期

关键词：

D O I：

10.1002/rcm.1290090606

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

High-performance liquid chromatography in combination with mass spectrometric detection (atmospheric-pressure chemical ionization, APCI) was used to determine various isoflavones. Negative-ion APCI ionization has proved to be a suitable technique for determining this class of natural. compound, as it provides quality mass spectra which give not only the molecular weight of the isoflavones, but also their molecular structures; consistent collision-induced dissociation pathways were elucidated and fragments are reported. Deuterium oxide was used to induce peak shifts in the mass spectra in order to determine the number of exchangeable hydrogen atoms in each molecule.

引用

页码：503 / 508

页数：6

共 20 条

[1] ADACHI T, 1994, ANAL SCI, V10, P437
[2] ARAMENDIA MA, IN PRESS J CHROMATOG
[3] DIRECT OBSERVATION OF A TERNARY COMPLEX BETWEEN THE DIMERIC ENZYME HIV-1 PROTEASE AND A SUBSTRATE-BASED INHIBITOR
BACA, M
KENT, SBH
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (10) : 3992 - 3993
[4] ELECTROSPRAY-IONIZATION MASS-SPECTROMETRY - A QUANTITATIVE SNAPSHOT ON AN INSTRUMENTAL BREAKTHROUGH
BRAUN, T
ZSINDELY, S
[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 1992, 11 (09) : 307 - 309
[5] Bruins AP, 1994, TRENDS ANAL CHEM, V13, P37
[6] BRUINS AP, 1994, TRENDS ANAL CHEM, V13, P2
[7] MULTIRESIDUE ANALYSIS OF SULFONAMIDES USING LIQUID-CHROMATOGRAPHY WITH ATMOSPHERIC-PRESSURE CHEMICAL-IONIZATION MASS-SPECTROMETRY
DOERGE, DR
BAJIC, S
LOWES, S
[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 1993, 7 (12) : 1126 - 1130
[8] ANALYSIS OF CLENBUTEROL IN HUMAN PLASMA USING LIQUID-CHROMATOGRAPHY ATMOSPHERIC-PRESSURE CHEMICAL-IONIZATION MASS-SPECTROMETRY
DOERGE, DR
BAJIC, S
LOWES, S
[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 1993, 7 (06) : 462 - 464
[9] ATMOSPHERIC-PRESSURE ION-SAMPLING SYSTEM FOR LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY ANALYSES ON A BENCHTOP MASS-SPECTROMETER
DUFFIN, KL
WACHS, T
HENION, JD
[J]. ANALYTICAL CHEMISTRY, 1992, 64 (01) : 61 - 68
[10] Harborne J.B., 1975, FLAVONOIDS

← 1 2 →