MONOZYGOTIC TWINS DISCORDANT FOR GASTROSCHISIS - CASE-REPORT AND REVIEW OF THE LITERATURE OF TWINS AND FAMILIAL OCCURRENCE OF GASTROSCHISIS

被引：25

作者：

BUGGE, M ^{[1
]}

PETERSEN, MB ^{[1
]}

CHRISTENSEN, MF ^{[1
]}

机构：

[1] HERNING HOSP,DEPT PEDIAT,HERNING,DENMARK

来源：

AMERICAN JOURNAL OF MEDICAL GENETICS | 1994年 / 52卷 / 02期

关键词：

GASTROSCHISIS; FAMILIAL OCCURRENCE; TWIN ZYGOSITY; DNA ANALYSIS; MICROSATELLITES;

D O I：

10.1002/ajmg.1320520219

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We describe a pair of monozygotic (MZ) female twins discordant for gastroschisis. To our knowledge, this is the first such case reported. The zygosity was verified by DNA analysis using highly polymorphic microsatellites. There was no family history of gastroschisis. During pregnancy there was no suspicion of any exposure responsible for the malformation. The number of twin cases described so far does not allow any conclusion as to hereditary factors in the cause of gastroschisis, but the number of families reported with familial gastroschisis suggests that the recurrence risk is higher than previously thought. (C) 1994 Wiley-Liss, Inc.

引用

页码：223 / 226

页数：4

共 42 条

[21] GENOMIC IMPRINTING, MONOZYGOTIC TWINNING, AND X-INACTIVATION [J].