BIOTRANSFORMATION OF SESQUITERPENES BY CULTURED-CELLS .2. BIOTRANSFORMATION OF GERMACRONE BY SUSPENSION-CULTURED CELLS

被引：19

作者：

SAKAMOTO, S

TSUCHIYA, N

KUROYANAGI, M

UENO, A

机构：

[1] School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka-shi, 422

来源：

PHYTOCHEMISTRY | 1994年 / 35卷 / 05期

关键词：

CELL SUSPENSION CULTURE; BIOTRANSFORMATION; SESQUITERPENE; GERMACRONE; GUAIANE; EUDESMANE; LONICERA JAPONICA; BUPLEURUM FALCATUM; POLYGONUM TINCTORIUM; SOLIDAGO ALTISSIMA;

D O I：

10.1016/S0031-9422(00)94823-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The transformation of germacrone, a 10-membered ring sesquiterpene, by suspension cultured cells of Lonicera japonica, Bupleurum falcatum, Polygonum tinctorium and Solidago altissima, was investigated. Germacrone was converted into several types of sesquiterpenes, such as guaiane, eudesmane and seco-guaiane and their structures were determined from spectral and chemical evidence. The configurations of some of the products were determined by CD spectroscopy. The differences of the kinds of products among the four suspension cultured cells is discussed.

引用

页码：1215 / 1219

页数：5

共 17 条

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