CONDENSATION REACTION BETWEEN 2,2-DIPHENYLTHIO-2,3-DIDEOXYRIBOSE AND SILYLATED PYRIMIDINE-BASES

被引：7

作者：

KAWAKAMI, H

EBATA, T

KOSEKI, K

MATSUMOTO, K

OKANO, K

MATSUSHITA, H

机构：

[1] Life Science Research Laboratory, Japan Tobacco Inc., Midori-ku, Yokohama, 6-2 Umegaoka

来源：

NUCLEOSIDES & NUCLEOTIDES | 1992年 / 11卷 / 09期

关键词：

D O I：

10.1080/07328319208021359

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The condensation reaction between 2,2-diphenylthio-2,3-dideoxyribose and silylated pyrimidine bases was examined. In the presence of TMSOTf as a catalyst, this reaction proceeded to give the nucleosides in the ratio of alpha : beta = 2 : 8. Each beta-anomer was converted to protected 2',3'-dideoxynucleosides.

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页码：1673 / 1682

页数：10

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