A PRACTICAL ROUTE TO EPIBATIDINE

被引：40

作者：

SZANTAY, C

KARDOSBALOGH, Z

MOLDVAI, I

SZANTAY, C

TEMESVARIMAJOR, E

BLASKO, G

机构：

[1] CHEM WORKS GEDEON RICHTER LTD,SPECT RES DEPT,H-1475 BUDAPEST,HUNGARY

[2] EGIS PHARMACEUT,H-1475 BUDAPEST,HUNGARY

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 19期

关键词：

ALKALOID; EPIBATIDINE; EPIBATIDINE ISOMER; ANALGESIC; PRACTICAL APPROACH;

D O I：

10.1016/S0040-4039(00)76859-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A practical synthetic approach to the alkaloid Epibatidine has been developed. This method is convenient and easy to scale up.

引用

收藏

页码：3171 / 3174

页数：4

相关论文

共 8 条

[1] MICHAEL ADDITIONS OF NITROALKANES TO ALPHA,BETA-UNSATURATED CARBONYL-COMPOUNDS USING KF BASIC ALUMINA
BERGBREITER, DE
LALONDE, JJ
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (08) : 1601 - 1603
[2] TOTAL SYNTHESIS OF EPIBATIDINE
BROKA, CA
[J]. TETRAHEDRON LETTERS, 1993, 34 (20) : 3251 - 3254
[3] A TOTAL SYNTHESIS OF (PLUS-OR-MINUS)-EPIBATIDINE
CLAYTON, SC
REGAN, AC
[J]. TETRAHEDRON LETTERS, 1993, 34 (46) : 7493 - 7496
[4] STEREOCONTROLLED TOTAL SYNTHESIS OF (+)-EPIBATIDINE AND (-)-EPIBATIDINE
COREY, EJ
LOH, TP
ACHYUTHARAO, S
DALEY, DC
SARSHAR, S
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (21) : 5600 - 5602
[5] THE SYNTHESIS OF (+)-EPIBATIDINE AND (-)-EPIBATIDINE
FLETCHER, SR
BAKER, R
CHAMBERS, MS
HOBBS, SC
MITCHELL, PJ
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1993, (15) : 1216 - 1218
[6] A VERSATILE TOTAL SYNTHESIS OF EPIBATIDINE AND ANALOGS
HUANG, DF
SHEN, TY
[J]. TETRAHEDRON LETTERS, 1993, 34 (28) : 4477 - 4480
[7] EPIBATIDINE - A NOVEL (CHLOROPYRIDYL)AZABICYCLOHEPTANE WITH POTENT ANALGESIC ACTIVITY FROM AN ECUADORIAN POISON FROG
SPANDE, TF
GARRAFFO, HM
EDWARDS, MW
YEH, HJC
PANNELL, L
DALY, JW
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (09) : 3475 - 3478
[8] ZIEGLER FE, 1969, TETRAHEDRON LETT, V14, P1097