TOTAL SYNTHESIS OF (-)-BALANOL

被引：96

作者：

LAMPE, JW

HUGHES, PF

BIGGERS, CK

SMITH, SH

HU, H

机构：

[1] Department of Chemical Research, Sphinx Pharmaceuticals Corporation, Durham, North Carolina 27717, Four University Place

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 18期

关键词：

D O I：

10.1021/jo00097a014

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(-)-Balanol, a fungal metabolite with potent protein kinase C inhibitory properties, has been prepared in a total synthesis which makes use of an anionic homo-Fries rearrangement approach to the benzophenone subunit and in which the azepane subunit is obtained from (2S,3R)-3-hydroxylysine.

引用

页码：5147 / 5148

页数：2

共 18 条

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