PEPTOID MIMICS OF A C-2-SYMMETRICAL INHIBITOR OF THE HIV-1 PROTEASE

被引：8

作者：

MAZALEYRAT, JP ^{[1
]}

RAGE, I ^{[1
]}

MOUNA, AM ^{[1
]}

SAVRDA, J ^{[1
]}

WAKSELMAN, M ^{[1
]}

BOULAY, R ^{[1
]}

LELIEVRE, Y ^{[1
]}

机构：

[1] RHONE POULENC RORER,F-94403 VITRY,FRANCE

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 11期

关键词：

D O I：

10.1016/S0960-894X(01)80345-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Compounds II, designed as retro peptoid mimics of a known potent C2-symmetric inhibitor I of the HIV protease, were synthesized in solution, using BOP as coupling reagent. They showed no significant inhibitory activity with respect to the HIV-1 protease.

引用

页码：1281 / 1284

页数：4

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