ENANTIOCONVERGENT SYNTHESIS OF A PROMISING HMG CO-A REDUCTASE INHIBITOR NK-104 FROM BOTH ENANTIOMERS OF EPICHLOROHYDRIN

被引：28

作者：

TAKANO, S

KAMIKUBO, T

SUGIHARA, T

SUZUKI, M

OGASAWARA, K

机构：

[1] Pharmaceutical Insutute, Tohoku University, Sendai, 980, Aobayama

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 02期

关键词：

D O I：

10.1016/S0957-4166(00)82337-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An enantioconvergent synthesis of (+)-NK-104 (3), a promising HMG Co-A reductase inhibitor, has been developed from both enantiomers of epichlorohydrin.

引用

页码：201 / 204

页数：4

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