学术探索
学术期刊
新闻热点
数据分析
智能评审

IMPORTANCE OF GENETIC-FACTORS IN THE REGULATION OF DIAZEPAM METABOLISM - RELATIONSHIP TO S-MEPHENYTOIN, BUT NOT DEBRISOQUIN, HYDROXYLATION PHENOTYPE

被引：263
作者：
BERTILSSON, L
HENTHORN, TK
SANZ, E
TYBRING, G
SAWE, J
VILLEN, T
机构：
来源：
CLINICAL PHARMACOLOGY & THERAPEUTICS | 1989年 / 45卷 / 04期
关键词：
D O I：
10.1038/clpt.1989.40
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：348 / 355
页数：8
相关论文
共 41 条
  • [11] DIAZEPAM EFFECTS AND KINETICS IN CAUCASIANS AND ORIENTALS
    GHONEIM, MM
    KORTTILA, K
    CHIANG, CK
    JACOBS, L
    SCHOENWALD, RD
    MEWALDT, SP
    KAYABA, KO
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 29 (06) : 749 - 756
  • [12] DIAZEPAM DISPOSITION DETERMINANTS
    GREENBLATT, DJ
    ALLEN, MD
    HARMATZ, JS
    SHADER, RI
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 1980, 27 (03) : 301 - 312
  • [13] BENZODIAZEPINE KINETICS - IMPLICATIONS FOR THERAPEUTICS AND PHARMACOGERIATRICS
    GREENBLATT, DJ
    DIVOLL, M
    ABERNETHY, DR
    OCHS, HR
    SHADER, RI
    [J]. DRUG METABOLISM REVIEWS, 1983, 14 (02) : 251 - 292
  • [14] GREENBLATT DJ, 1981, BR J CLIN PHARM, V1, P35
  • [15] INABA T, 1985, DRUG METAB DISPOS, V13, P443
  • [16] PHARMACOKINETIC MODEL FOR DIAZEPAM AND ITS MAJOR METABOLITE DESMETHYLDIAZEPAM FOLLOWING DIAZEPAM ADMINISTRATION
    JACK, ML
    COLBURN, WA
    [J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1983, 72 (11) : 1318 - 1323
  • [17] GENETIC-POLYMORPHISM OF MEPHENYTOIN P(4')-HYDROXYLATION - DIFFERENCE BETWEEN ORIENTALS AND CAUCASIANS
    JURIMA, M
    INABA, T
    KADAR, D
    KALOW, W
    [J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1985, 19 (04) : 483 - 487
  • [18] THE GENETIC-DEFECT OF MEPHENYTOIN HYDROXYLATION
    KALOW, W
    [J]. XENOBIOTICA, 1986, 16 (05) : 379 - 389
  • [19] ALTERED ELIMINATION OF DESMETHYLDIAZEPAM IN THE ELDERLY
    KLOTZ, U
    MULLERSEYDLITZ, P
    [J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1979, 7 (01) : 119 - 120
  • [20] KLOTZ U, 1977, CLIN PHARMACOL THER, V21, P430
12345