REGIOSELECTIVITY AND STEREOSELECTIVITY OF VARIOUS FORMS OF PURIFIED CYTOCHROME-P-450 IN METABOLISM OF BENZO[A]PYRENE AND (-) TRANS-7,8-DIHYDROXY-7,8-DIHYDROBENZO[A]PYRENE AS SHOWN BY PRODUCT FORMATION AND BINDING TO DNA

被引：122

作者：

DEUTSCH, J ^{[1
]}

LEUTZ, JC ^{[1
]}

YANG, SK ^{[1
]}

GELBOIN, HV ^{[1
]}

CHIANG, YL ^{[1
]}

VATSIS, KP ^{[1
]}

COON, MJ ^{[1
]}

机构：

[1] UNIV MICHIGAN, SCH MED, DEPT BIOL CHEM, ANN ARBOR, MI 48109 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1978年 / 75卷 / 07期

关键词：

D O I：

10.1073/pnas.75.7.3123

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：3123 / 3127

页数：5

共 43 条

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[36] POSITION-SPECIFIC OXYGENATION OF BENZO[A]PYRENE BY DIFFERENT FORMS OF PURIFIED CYTOCHROME-P-450 FROM RABBIT LIVER
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[37] ENZYMATIC CONVERSION OF BENZO[A]PYRENE LEADING PREDOMINANTLY TO DIOL-EPOXIDE R-7,T-8-DIHYDROXY-T-9,10-OXY-7,8,9,10-TETRAHYDROBENZO[A]PYRENE THROUGH A SINGLE ENANTIOMER OF R-7,T-8-DIHYDROXY-7,8-DIHYDROBENZO[A]PYRENE
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (08) : 2594 - 2598
[38] YANG SK, 1976, CANCER RES, V36, P4185
[39] STEREOCHEMISTRY OF HYDROLYSIS PRODUCTS AND THEIR ACETONIDES OF 2 STEREOISOMERIC BENZO[A]PYRENE 7,8-DIOL 9,10-EPOXIDES
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[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1977, 99 (15) : 5124 - 5130
[40] YANG SK, 1976, BIOCHEM PHARMACOL, V25, P2221, DOI 10.1016/0006-2952(76)90138-6

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