THEORY OF CHIRAL SEPARATION IN CAPILLARY ELECTROPHORESIS

被引:176
作者
WREN, SAC
机构
[1] Pharmaceutical Department, Zeneca Pharmaceuticals, Macclesfield
来源
JOURNAL OF CHROMATOGRAPHY | 1993年 / 636卷 / 01期
关键词
D O I
10.1016/0021-9673(93)80056-E
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The resolution of a pair of enantiomers in chiral capillary electrophoresis (CE) is described by the use of a simple model. The model shows the importance of maximising the electrophoretic mobility difference between the two enantiomers, and also the influence of electroosmotic mobility. The theory is supported by results obtained with ephedrine, atenolol and practolol.
引用
收藏
页码:57 / 62
页数:6
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