SYNTHESIS OF HYDROLYTIC ENZYMES DURING PRODUCTION OF TYLOSIN BY STREPTOMYCES-FRADIAE

被引：16

作者：

BRAHIMIHORN, MC ^{[1
]}

LUO, SH ^{[1
]}

WANG, SL ^{[1
]}

GAU, SW ^{[1
]}

MOU, DG ^{[1
]}

机构：

[1] DEV CTR BIOTECHNOL,MICROBIOL,81 CHANG HSING ST,TAIPEI,TAIWAN

来源：

JOURNAL OF INDUSTRIAL MICROBIOLOGY | 1992年 / 10卷 / 01期

关键词：

TYLOSIN PRODUCTION; STREPTOMYCES-FRADIAE; AMYLASE; PROTEASE; LIPASE; ESTERASE;

D O I：

10.1007/BF01583630

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The exposure of a wild-type tylosin producing strain of Streptemyces fradiae to mutagenic agents resulted in the isolation of several tylosin over-producing strains. Examination of three mutants, T4310, 612 and 3204 showed that improved tylosin production was associated with increased hydrolytic enzyme activity and cell growth. The wild-type strain showed lower levels of hydrolytic activity including, protease, amylase, lipase and esterase activities and attained a lower cell density than the mutants.

引用

页码：25 / 30

页数：6