BIOCATALYTIC RESOLUTION OF 2,3-EPOXYALCOHOLS IN ORGANIC-SOLVENTS

被引：14

作者：

KANERVA, LT

VANTTINEN, E

机构：

[1] Department of Chemistry, University of Turku

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 01期

关键词：

D O I：

10.1016/S0957-4166(00)86018-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The PPL-catalysed resolution of 3-substituted cis-2,3-epoxyalcohols has been successfully performed in toluene and in THF. Lower enantioselectivities were observed for the trans-isomers. A substituent at the position 3 of an epoxyalcohol controls the enantiomeric discrimination, the 3R centre always occuring in the enantiomer which reacts faster.

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页码：85 / 90

页数：6

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