A VARIANT T(14-17) IN ACUTE PROMYELOCYTIC LEUKEMIA - POSITIVE RESPONSE TO RETINOIC ACID TREATMENT

被引：7

作者：

CIGUDOSA, JC

CALASANZ, MJ

ODERO, MD

MARIN, J

BENGOECHEA, E

GULLON, A

机构：

[1] UNIV NAVARRA,DEPT GENET,E-31080 PAMPLONA,SPAIN

[2] UNIV LA LAGUNA,FAC MED,CYTOGENET SERV,LA LAGUNA,SPAIN

[3] HOSP NUESTRA SENORA ARANZAZU,SERV HEMATOL,SAN SEBASTIAN,SPAIN

来源：

CANCER GENETICS AND CYTOGENETICS | 1995年 / 80卷 / 02期

关键词：

D O I：

10.1016/0165-4608(94)00182-B

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We present a case of acute promyelocytic leukemia (APL) carrying an atypical translocation involving chromosomes 14 and 17. This translocation could be considered a variant of the APL-specific t(15;17). Positive response to retinoic acid treatment suggests molecular rearrangement of retinoic acid receptor alpha.

引用

页码：160 / 161

页数：2

共 10 条

[1] TRANSLOCATION (8,17)(P21,Q21), A POSSIBLE VARIANT OF T(15,17), IN ACUTE PROMYELOCYTIC LEUKEMIA
MIURA, I
NISHINARI, T
HASHIMOTO, K
NIMURA, T
MIURA, S
MIURA, AB
[J]. CANCER GENETICS AND CYTOGENETICS, 1994, 72 (01) : 75 - 77
[2] NAJFELD V, 1989, CANCER GENET CYTOGEN, V33, P103
[3] DETECTION OF THE PML/RAR-ALPHA FUSION GENE IN ACUTE PROMYELOCYTIC LEUKEMIA WITH A COMPLEX TRANSLOCATION INVOLVING CHROMOSOME-15, CHROMOSOME-17, AND CHROMOSOME-18
OGAWA, S
MITANI, K
SATO, Y
SUGIMOTO, K
TOYOSHIMA, H
MANO, H
TAKAKU, F
YAZAKI, Y
HIRAI, H
[J]. CANCER GENETICS AND CYTOGENETICS, 1993, 69 (02) : 113 - 117
[4] REPORT OF A VARIANT T(1-15-17)(P36-Q22-Q21.1) IN A PATIENT WITH ACUTE PROMYELOCYTIC LEUKEMIA
OSELLA, P
WYANDT, H
VOSBURGH, E
MILUNSKY, A
[J]. CANCER GENETICS AND CYTOGENETICS, 1991, 57 (02) : 201 - 207
[5] PALKA G, 1987, ANN GENET-PARIS, V30, P39
[6] ROWLEY JD, 1977, LANCET, V1, P549
[7] SANDBERG AA, 1990, CHROMOSOMES HUMAN CA
[8] ACUTE PROMYELOCYTIC LEUKEMIA - REPORT OF A VARIANT TRANSLOCATION, T(1-17)
SCHWARTZ, JG
CLARE, N
HANSEN, K
BRITTON, H
MANHOFF, L
[J]. CANCER GENETICS AND CYTOGENETICS, 1986, 20 (1-2) : 89 - 93
[9] ACUTE PROMYELOCYTIC LEUKEMIA
WARRELL, RP
DETHE, H
WANG, ZY
DEGOS, L
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1993, 329 (03) : 177 - 189
[10] YAMADA K, 1983, CANCER GENET CYTOGEN, V2, P93

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