SEMISYNTHETIC MODIFICATION OF HYGROMYCIN-A .2. SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF ARYL ANALOGS

被引：11

作者：

HECKER, SJ

COOPER, CB

BLAIR, KT

LILLEY, SC

MINICH, ML

WERNER, KM

机构：

[1] Pfizer Inc, Central Research Division, Groton

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 02期

关键词：

D O I：

10.1016/S0960-894X(01)80895-7

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Syntheses of analogs exploring the SAR of the aryl region of hygromycin A are described. Antibacterial activities against Serpulina (Tresponema) hyodysenteriae and Pasteurella multocida, two key animal health pathogens, are reported.

引用

页码：289 / 294

页数：6

共 12 条

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