PACLITAXEL AND DOCETAXEL PHOTOAFFINITY LABELS

被引:8
作者
GEORG, GI [1 ]
BOGE, TC [1 ]
PARK, H [1 ]
HIMES, RH [1 ]
机构
[1] UNIV KANSAS, DEPT BIOCHEM, LAWRENCE, KS 66045 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/0960-894X(95)00083-6
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The synthesis and in vitro evaluation of four novel 3-azidobenzoyl photoaffinity analogues of paclitaxel and docetaxel is detailed. Due to their good to excellent ability to stimulate the assembly of microtubules they have potential as photoaffinity probes.
引用
收藏
页码:615 / 620
页数:6
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