PACLITAXEL AND DOCETAXEL PHOTOAFFINITY LABELS

被引：8

作者：

GEORG, GI ^{[1
]}

BOGE, TC ^{[1
]}

PARK, H ^{[1
]}

HIMES, RH ^{[1
]}

机构：

[1] UNIV KANSAS, DEPT BIOCHEM, LAWRENCE, KS 66045 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1995年 / 5卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0960-894X(95)00083-6

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The synthesis and in vitro evaluation of four novel 3-azidobenzoyl photoaffinity analogues of paclitaxel and docetaxel is detailed. Due to their good to excellent ability to stimulate the assembly of microtubules they have potential as photoaffinity probes.

引用

收藏

页码：615 / 620

页数：6

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