ENZYME AIDED SYNTHESIS OF D-MYO-INOSITOL 1,4,5-TRISPHOSPHATE

被引：18

作者：

LING, L ^{[1
]}

OZAKI, S ^{[1
]}

机构：

[1] EHIME UNIV,FAC ENGN,DEPT APPL CHEM,MATSUYAMA,EHIME 790,JAPAN

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 15期

关键词：

D O I：

10.1016/S0040-4039(00)60452-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Racemic 2,3-mono-O-cyclohexylidene-myo-inositol (1) was efficiently resolved by enzymatic esterification in organic solvent and a new practical route for synthesis of D-myo-inositol 1,4,5-trisphosphate (13) started from the optically pure D-2,3-mono-O-cydobexylidene-myo-inositol (3) is described.

引用

页码：2501 / 2504

页数：4

共 17 条

[1] PRACTICAL SYNTHESIS OF ENANTIOMERICALLY PURE MYOINOSITOL DERIVATIVES [J].

BRUZIK, KS ;

MYERS, J ;

TSAI, MD .

TETRAHEDRON LETTERS, 1992, 33 (08) :1009-1012

[2] EFFICIENT AND SYSTEMATIC SYNTHESES OF ENANTIOMERICALLY PURE AND REGIOSPECIFICALLY PROTECTED MYOINOSITOLS [J].

BRUZIK, KS ;

TSAI, MD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (16) :6361-6374

[3] GENERAL-ASPECTS AND OPTIMIZATION OF ENANTIOSELECTIVE BIOCATALYSIS IN ORGANIC-SOLVENTS - THE USE OF LIPASES [J].

CHEN, CS ;

SIH, CJ .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1989, 28 (06) :695-707

[4]

John V. T., 1991, BIOCATAL IND, P193

[5] ASYMMETRIC TRANSFORMATIONS CATALYZED BY ENZYMES IN ORGANIC-SOLVENTS [J].

KLIBANOV, AM .

ACCOUNTS OF CHEMICAL RESEARCH, 1990, 23 (04) :114-120

[6] AN EFFICIENT SYNTHESIS OF OPTICALLY-ACTIVE D-MYO-INOSITOL 1,4,5-TRIPHOSPHATE [J].

LIU, YC ;

CHEN, CS .

TETRAHEDRON LETTERS, 1989, 30 (13) :1617-1620

[7]

MASSY DJR, 1990, HELV CHIM ACTA, V73, P1037

[8] SYNTHESIS AND SOME PROPERTIES OF D-MYO-INOSITOL 1,4,5-TRIS(DIHYDROGEN PHOSPHATE) [J].

OZAKI, S ;

KONDO, Y ;

SHIOTANI, N ;

OGASAWARA, T ;

WATANABE, Y .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1992, (06) :729-737

[9]

OZAKI S, 1986, TETRAHEDRON LETT, V27, P3159

[10] SOME RECENT DEVELOPMENTS IN THE USE OF ENZYME CATALYZED-REACTIONS IN ORGANIC-SYNTHESIS [J].

ROBERTS, SM ;

TURNER, NJ .

JOURNAL OF BIOTECHNOLOGY, 1992, 22 (03) :227-244

← 1 2 →