NUCLEOTIDE-SEQUENCE OF THE 5'-FLANKING REGION OF THE RAT TYPE-II HEXOKINASE GENE

被引：13

作者：

ICHIHARA, J ^{[1
]}

SHINOHARA, Y ^{[1
]}

KOGURE, K ^{[1
]}

TERADA, H ^{[1
]}

机构：

[1] UNIV TOKUSHIMA,FAC PHARMACEUT SCI,TOKUSHIMA 770,JAPAN

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1995年 / 1260卷 / 03期

关键词：

5'-FLANKING REGION; PUTATIVE TRANSCRIPTIONAL FACTOR BINDING SITE; TYPE II HEXOKINASE GENE; (RAT);

D O I：

10.1016/0167-4781(94)00226-S

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In a previous study, we found that the steady state transcript level of type II hexokinase was specifically and remarkably elevated in rat hepatoma AH130 cells. To determine the molecular mechanism of transcriptional control of the type II hexokinase gene, we examined the nucleotide sequence of its S-flanking region and analyzed putative transcription factor binding sites. We also examined the type II hexokinase promoter activity by the chloramphenicol acetyltransferase (CAT) assay.

引用

页码：365 / 368

页数：4

共 20 条

[11] Sambrook J., 1989, MOL CLONING LAB MANU
[12] SATO S, 1969, CANCER RES, V29, P1437
[13] COMPLETE AMINO-ACID SEQUENCE OF RAT-BRAIN HEXOKINASE, DEDUCED FROM THE CLONED CDNA, AND PROPOSED STRUCTURE OF A MAMMALIAN HEXOKINASE
SCHWAB, DA
WILSON, JE
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (08) : 2563 - 2567
[14] COMPLETE AMINO-ACID-SEQUENCE OF THE TYPE-III ISOZYME OF RAT HEXOKINASE, DEDUCED FROM THE CLONED CDNA
SCHWAB, DA
WILSON, JE
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1991, 285 (02) : 365 - 370
[15] SCHWAB DA, 1988, J BIOL CHEM, V263, P3220
[16] REMARKABLY ENHANCED EXPRESSION OF THE TYPE-II HEXOKINASE IN RAT HEPATOMA-CELL LINE AH130
SHINOHARA, Y
ICHIHARA, J
TERADA, H
[J]. FEBS LETTERS, 1991, 291 (01) : 55 - 57
[17] TRANSPORT AND PHOSPHORYLATION OF HEXOSES IN NORMAL AND ROUS-SARCOMA VIRUS-TRANSFORMED CHICK-EMBRYO FIBROBLASTS
SINGH, M
SINGH, VN
AUGUST, JT
HORECKER, BL
[J]. JOURNAL OF CELLULAR PHYSIOLOGY, 1978, 97 (03) : 285 - 292
[18] COMPLETE AMINO-ACID-SEQUENCE OF THE TYPE-II ISOZYME OF RAT HEXOKINASE, DEDUCED FROM THE CLONED CDNA - COMPARISON WITH A HEXOKINASE FROM NOVIKOFF ASCITES TUMOR
THELEN, AP
WILSON, JE
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1991, 286 (02) : 645 - 651
[19] VERHAGEN JN, 1985, CANCER, V55, P1519, DOI 10.1002/1097-0142(19850401)55:7<1519::AID-CNCR2820550718>3.0.CO
[20] 2-K

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