DISCOVERY OF CP-96,345 AND ITS CHARACTERIZATION IN DISEASE-MODELS INVOLVING SUBSTANCE-P

被引：14

作者：

LOWE, JA ^{[1
]}

DROZDA, SE ^{[1
]}

SNIDER, RM ^{[1
]}

LONGO, KP ^{[1
]}

ZORN, SH ^{[1
]}

JACKSON, ER ^{[1
]}

MORRONE, J ^{[1
]}

MCLEAN, S ^{[1
]}

BRYCE, DK ^{[1
]}

BORDNER, J ^{[1
]}

NAGAHISA, A ^{[1
]}

KANAI, Y ^{[1
]}

SUGA, O ^{[1
]}

TSUCHIYA, M ^{[1
]}

机构：

[1] PFIZE INC,DIV CENT RES,DEPT MED BIOL,AICHI,JAPAN

来源：

REGULATORY PEPTIDES | 1993年 / 46卷 / 1-2期

关键词：

CP-96,345; SUBSTANCE-P; DISEASE MODEL; INFLAMMATION; PAIN;

D O I：

10.1016/0167-0115(93)90006-T

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：20 / 23

页数：4

共 12 条

[1] INVESTIGATION INTO SPECIES VARIANTS IN TACHYKININ NK1 RECEPTORS BY USE OF THE NONPEPTIDE ANTAGONIST, CP-96,345
BERESFORD, IJM
BIRCH, PJ
HAGAN, RM
IRELAND, SJ
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1991, 104 (02) : 292 - 293
[2] CIGARETTE SMOKE-INDUCED AIRWAY EDEMA IS BLOCKED BY THE NK1 ANTAGONIST, CP-96,345
DELAYGOYET, P
LUNDBERG, JM
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1991, 203 (01) : 157 - 158
[3] INHIBITION OF NEUROGENIC PLASMA EXUDATION IN GUINEA-PIG AIRWAYS BY CP-96,345, A NEW NONPEPTIDE NK(1) RECEPTOR ANTAGONIST
LEI, YH
BARNES, PJ
ROGERS, DF
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1992, 105 (02) : 261 - 262
[4] THE NONPEPTIDE TACHYKININ ANTAGONIST, CP-96,345, IS A POTENT INHIBITOR OF NEUROGENIC INFLAMMATION
LEMBECK, F
DONNERER, J
TSUCHIYA, M
NAGAHISA, A
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1992, 105 (03) : 527 - 530
[5] THE DISCOVERY OF (2S,3S)-CIS-2-(DIPHENYLMETHYL)-N-[(2-METHOXYPHENYL)METHYL]-1-AZABICYCLO[2.2.2]OCTAN-3-AMINE AS A NOVEL, NONPEPTIDE SUBSTANCE-P ANTAGONIST
LOWE, JA
DROZDA, SE
SNIDER, RM
LONGO, KP
ZORN, SH
MORRONE, J
JACKSON, ER
MCLEAN, S
BRYCE, DK
BORDNER, J
NAGAHISA, A
KANAI, Y
SUGA, O
TSUCHIYA, M
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (14) : 2591 - 2600
[6] ANTIINFLAMMATORY AND ANALGESIC ACTIVITY OF A NONPEPTIDE SUBSTANCE-P RECEPTOR ANTAGONIST
NAGAHISA, A
KANAI, Y
SUGA, O
TANIGUCHI, K
TSUCHIYA, M
LOWE, JA
HESS, HJ
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1992, 217 (2-3) : 191 - 195
[7] NONSPECIFIC ACTIVITY OF (+/-)-CP-96,345 IN MODELS OF PAIN AND INFLAMMATION
NAGAHISA, A
ASAI, R
KANAI, Y
MURASE, A
TSUCHIYANAKAGAKI, M
NAKAGAKI, T
SHIEH, TC
TANIGUCHI, K
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1992, 107 (02) : 273 - 275
[8] NOVEL SUBSTANCE-P ANTAGONIST, CP-96,345, BLOCKS RESPONSES OF CAT SPINAL DORSAL HORN NEURONS TO NOXIOUS CUTANEOUS STIMULATION AND TO SUBSTANCE-P
RADHAKRISHNAN, V
HENRY, JL
[J]. NEUROSCIENCE LETTERS, 1991, 132 (01) : 39 - 43
[9] THE SUBSTANCE-P RECEPTOR ANTAGONIST CP-96,345 INTERACTS WITH CA-2+ CHANNELS
SCHMIDT, AW
MCLEAN, S
HEYM, J
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1992, 219 (03) : 491 - 492
[10] EFFECT OF CP-96,345, A NONPEPTIDE SUBSTANCE-P RECEPTOR ANTAGONIST, ON SALIVATION IN RATS
SNIDER, RM
LONGO, KP
DROZDA, SE
LOWE, JA
LEEMAN, SE
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (22) : 10042 - 10044

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