ASYMMETRIC-SYNTHESIS OF NAPROXEN BY A NEW HETEROGENEOUS CATALYST

被引：53

作者：

WAN, KT ^{[1
]}

DAVIS, ME ^{[1
]}

机构：

[1] CALTECH,DIV CHEM & CHEM ENGN,PASADENA,CA 91125

来源：

JOURNAL OF CATALYSIS | 1995年 / 152卷 / 01期

关键词：

D O I：

10.1006/jcat.1995.1056

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A new heterogeneous, asymmetric catalyst is described. The catalyst is a modified version of the supported aqueous-phase catalyst reported previously (Wan and Davis, J. Catal. 148, 1 (1994)); ethylene glycol is used in place of water as the hydrophilic phase. Both the enantioselectivity and the activity of this new heterogeneous catalyst are comparable to the homogeneous analogue in neat methanol (or ethylene glycol); e.e.'s are 95.7% vs 96.1% and t.o.f.'s are 40.7 hr(-1) vs 131.0 hr(-1), respectively. Recycling of the catalyst is possible without leaching of ruthenium at a detection limit of 32 ppb. (C) 1995 Academic Press, Inc.

引用

页码：25 / 30

页数：6

共 9 条

[1] HYDROFORMYLATION BY SUPPORTED AQUEOUS-PHASE CATALYSIS - A NEW CLASS OF HETEROGENEOUS CATALYSTS [J].