ARYLHYDROXAMIC ACID BIOACTIVATION VIA ACYL GROUP TRANSFER - STRUCTURAL REQUIREMENTS FOR TRANSACYLATING AND ELECTROPHILE-GENERATING ACTIVITY OF N-(2-FLUORENYL)HYDROXAMIC ACIDS AND RELATED-COMPOUNDS

被引：23

作者：

YEH, HM

HANNA, PE

机构：

[1] UNIV MINNESOTA,DEPT MED CHEM,MINNEAPOLIS,MN 55455

[2] UNIV MINNESOTA,DEPT PHARMACOL,MINNEAPOLIS,MN 55455

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1982年 / 25卷 / 07期

关键词：

D O I：

10.1021/jm00349a015

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：842 / 846

页数：5

共 22 条

[1] ARYLHYDROXAMIC ACID N,O-ACYLTRANSFERASE - APPARENT SUICIDE INACTIVATION BY CARCINOGENIC N-ARYLHYDROXAMIC ACIDS [J].

BANKS, RB ;

HANNA, PE .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1979, 91 (04) :1423-1429

[2] ELECTROPHILIC N-ACETOXYAMINOARENES DERIVED FROM CARCINOGENIC N-HYDROXY-N-ACETYLAMINOARENES BY ENZYMATIC DEACETYLATION AND TRANSACETYLATION IN LIVER [J].

BARTSCH, H ;

DWORKIN, M ;

MILLER, JA ;

MILLER, EC .

BIOCHIMICA ET BIOPHYSICA ACTA, 1972, 286 (02) :272-298

[3] FORMATION OF ELECTROPHILIC N-ACETOXYARYLAMINES IN CYTOSOLS FROM RAT MAMMARY-GLAND AND OTHER TISSUES BY TRANSACETYLATION FROM CARCINOGEN N-HYDROXY-4-ACETYLAMINOBIPHENYL [J].

BARTSCH, H ;

DWORKIN, C ;

MILLER, EC ;

MILLER, JA .

BIOCHIMICA ET BIOPHYSICA ACTA, 1973, 304 (01) :42-55

[4]

BELAND FA, 1980, CANCER RES, V40, P834

[5] ACETYL TRANSFER IN ARYLAMINE METABOLISM [J].

BOOTH, J .

BIOCHEMICAL JOURNAL, 1966, 100 (03) :745-&

[6] SYNTHESIS AND SOME REACTIONS OF N-HYDROXYCARBAMATES [J].

BOYLAND, E ;

NERY, R .

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1966, (03) :346-+

[7]

GLOWINSKI IB, 1980, J BIOL CHEM, V255, P7883

[8]

HANNA PE, 1982, MOL PHARMACOL, V21, P159

[9] METABOLIC N-HYDROXYLATION - USE OF SUBSTITUENT VARIATION TO MODULATE THE INVITRO BIOACTIVATION OF 4-ACETAMIDOSTILBENES [J].

HANNA, PE ;

GAMMANS, RE ;

SEHON, RD ;

LEE, MK .

JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (09) :1038-1044

[10]

KING CM, 1974, CANCER RES, V34, P1503

← 1 2 3 →