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CROHNS-DISEASE AND CYSTIC-FIBROSIS

被引：78
作者：
LLOYDSTILL, JD
机构：
[1] From the Children's Memorial Hospital, Northwestern University, Chicago, Illinois
来源：
DIGESTIVE DISEASES AND SCIENCES | 1994年 / 39卷 / 04期
关键词：
CYSTIC FIBROSIS; INFLAMMATORY BOWEL DISEASE; CROHNS DISEASE; INTESTINAL CANCER;
D O I：
10.1007/BF02087437
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Advances in investigative techniques have led to increasing reports of Crohn's disease in CF patients. A retrospective review of the literature on IBD in CF showed findings characterized by ileocolitis with fistula formation; 83% required surgery. A prospective survey of 11, 321 CF patients attending 49 CIF centers revealed 28 with IBD (25 Crohn's, three ulcerative colitis), ages 4-20 years, mean 15.6 years. The prevalence rate of IBD (247/10(5)) was 7x controls and was accounted for by Crohn's disease (221/10(5)) which was 17x controls. The mechanisms that predispose CF patients to Crohn's disease are discussed.
引用
收藏
页码：880 / 885
页数：6
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