CROHNS-DISEASE AND CYSTIC-FIBROSIS

被引：78

作者：

LLOYDSTILL, JD

机构：

[1] From the Children's Memorial Hospital, Northwestern University, Chicago, Illinois

来源：

DIGESTIVE DISEASES AND SCIENCES | 1994年 / 39卷 / 04期

关键词：

CYSTIC FIBROSIS; INFLAMMATORY BOWEL DISEASE; CROHNS DISEASE; INTESTINAL CANCER;

D O I：

10.1007/BF02087437

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Advances in investigative techniques have led to increasing reports of Crohn's disease in CF patients. A retrospective review of the literature on IBD in CF showed findings characterized by ileocolitis with fistula formation; 83% required surgery. A prospective survey of 11, 321 CF patients attending 49 CIF centers revealed 28 with IBD (25 Crohn's, three ulcerative colitis), ages 4-20 years, mean 15.6 years. The prevalence rate of IBD (247/10(5)) was 7x controls and was accounted for by Crohn's disease (221/10(5)) which was 17x controls. The mechanisms that predispose CF patients to Crohn's disease are discussed.

引用

页码：880 / 885

页数：6