Characterization of the limited specificity of antigen recognition in earthworms

被引：7

作者：

Bilej, M ^{[1
]}

Tuckova, L ^{[1
]}

Romanovsky, A ^{[1
]}

机构：

[1] CHARLES UNIV,FAC SCI,CR-12800 PRAGUE 2,CZECH REPUBLIC

来源：

FOLIA MICROBIOLOGICA | 1995年 / 40卷 / 04期

关键词：

D O I：

10.1007/BF02814753

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Earthworms respond to parenteral stimulation with a protein antigen by the formation of an antigen-binding protein. Earthworms were parenterally stimulated with different proteins and the protein binding was estimated in vitro on both humoral and cellular levels. The binding was significantly higher when the same protein was used for in vivo stimulation. The degree of specificity of the antigen-binding protein after the secondary in vivo challenge increased, but even so it was considerably lower than that of vertebrate immunoglobulins.

引用

页码：436 / 440

页数：5

共 13 条

[1] REPEATED ANTIGENIC CHALLENGE INDUCES EARTHWORM CELOMOCYTE PROLIFERATION [J].