STRUCTURE OF MOUSE MYELIN-ASSOCIATED GLYCOPROTEIN GENE

被引：25

作者：

NAKANO, R ^{[1
]}

FUJITA, N ^{[1
]}

SATO, S ^{[1
]}

INUZUKA, T ^{[1
]}

SAKIMURA, K ^{[1
]}

ISHIGURO, H ^{[1
]}

MISHINA, M ^{[1
]}

MIYATAKE, T ^{[1
]}

机构：

[1] NIIGATA UNIV,BRAIN RES INST,DEPT NEUROPHARMACOL,NIIGATA 951,JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1991年 / 178卷 / 01期

关键词：

CELL-ADHESION MOLECULE; BASIC-PROTEIN GENE; MESSENGER-RNA; QUAKING MOUSE; CDNA CLONING; SUPERFAMILY; ELEMENTS; BRAIN;

D O I：

10.1016/0006-291X(91)91811-P

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The mouse myelin-associated glycoprotein gene was isolated from a mouse gene library. This gene was split into 13 exons distributed about 15 kb in length. Each extracellular immunoglobulin-related domain was encoded by a single exon, and RNA splicing between those exons occurred between the first and second nucleotides of the junctional codon, the features of which are conserved in most of the genes of the immunoglobulin superfamily. The sequence of the 5′-flanking region appeared to have some regions homologous to other myelin proteins, which suggested that they were possible cis-elements for specific expression of oligodendrocytes. © 1991.

引用

页码：282 / 290

页数：9

共 24 条

[1] MOLECULAR-CLONING AND PRIMARY STRUCTURE OF MYELIN-ASSOCIATED GLYCOPROTEIN [J].

ARQUINT, M ;

RODER, J ;

CHIA, LS ;

DOWN, J ;

WILKINSON, D ;

BAYLEY, H ;

BRAUN, P ;

DUNN, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (02) :600-604

[2] CONSERVED MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II BOX-X AND BOX-Y ARE TRANSCRIPTIONAL CONTROL ELEMENTS AND SPECIFICALLY BIND NUCLEAR PROTEINS [J].

DORN, A ;

DURAND, B ;

MARFING, C ;

LEMEUR, M ;

BENOIST, C ;

MATHIS, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (17) :6249-6253

[3]

EVANS GA, 1987, MOL NEUROBIOLOGY REC, P225

[4]

FRAIL DE, 1984, J BIOL CHEM, V259, P4857

[5] DEVELOPMENTALLY REGULATED ALTERNATIVE SPLICING OF BRAIN MYELIN-ASSOCIATED GLYCOPROTEIN MESSENGER-RNA IS LACKING IN THE QUAKING MOUSE [J].

FUJITA, N ;

SATO, S ;

KURIHARA, T ;

INUZUKA, T ;

TAKAHASHI, Y ;

MIYATAKE, T .

FEBS LETTERS, 1988, 232 (02) :323-327

[6] CDNA CLONING OF MOUSE MYELIN-ASSOCIATED GLYCOPROTEIN - A NOVEL ALTERNATIVE SPLICING PATTERN [J].

FUJITA, N ;

SATO, S ;

KURIHARA, T ;

KUWANO, R ;

SAKIMURA, K ;

INUZUKA, T ;

TAKAHASHI, Y ;

MIYATAKE, T .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1989, 165 (03) :1162-1169

[7] THE LARGE ISOFORM OF MYELIN-ASSOCIATED GLYCOPROTEIN IS SCARCELY EXPRESSED IN THE QUAKING MOUSE-BRAIN [J].

FUJITA, N ;

SATO, S ;

ISHIGURO, H ;

INUZUKA, T ;

BABA, H ;

KURIHARA, T ;

TAKAHASHI, Y ;

MIYATAKE, T .

JOURNAL OF NEUROCHEMISTRY, 1990, 55 (03) :1056-1059

[8] INDUCTION OF MYELIN-ASSOCIATED GLYCOPROTEIN MESSENGER-RNA IN EXPERIMENTAL REMYELINATION [J].

FUJITA, N ;

ISHIGURO, H ;

SATO, S ;

KURIHARA, T ;

KUWANO, R ;

SAKIMURA, K ;

TAKAHASHI, Y ;

MIYATAKE, T .

BRAIN RESEARCH, 1990, 513 (01) :152-155

[9] THE GROWING IMMUNOGLOBULIN GENE SUPERFAMILY [J].

HUNKAPILLER, T ;

HOOD, L .

NATURE, 1986, 323 (6083) :15-16

[10] MYELIN PROTEOLIPID PROTEIN GENE STRUCTURE AND ITS REGULATION OF EXPRESSION IN NORMAL AND JIMPY MUTANT MICE [J].

IKENAKA, K ;

FURUICHI, T ;

IWASAKI, Y ;

MORIGUCHI, A ;

OKANO, H ;

MIKOSHIBA, K .

JOURNAL OF MOLECULAR BIOLOGY, 1988, 199 (04) :587-596

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