A NEW VERSATILE FLUORINATED-C(4) CHIRON

被引：17

作者：

ARNONE, A

BRAVO, P

CAVICCHIO, G

FRIGERIO, M

MARCHETTI, V

VIANI, F

ZAPPALA, C

机构：

[1] POLITECN MILAN,CNR,CTR STUDIO SOSTANZE ORGAN NAT,DIPARTIMENTO CHIM,I-20133 MILAN,ITALY

[2] UNIV LAQUILA,DIPARTIMENTO GASTROENTEROL,I-67100 LAQUILA,ITALY

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 38期

关键词：

D O I：

10.1016/S0040-4039(00)61160-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Optically pure 2-(fluoromethyl)-2-[(4-methylphenylsulphinyl)methyl]oxirane has been obtained in good yield and with high d.e. by reacting diazomethane with optically pure 1-fluoro-3-(4-methylphenylsulphinyl)propan-2-one. Regio- and stereo-selective openings of oxirane ring performed with selected nucleophiles afforded several useful derivatives.

引用

页码：5609 / 5612

页数：4

共 28 条

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