SYNTHESIS OF A NOVEL ANALOG OF SIALYL-LEWIS-X

被引：34

作者：

PRODGER, JC ^{[1
]}

BAMFORD, MJ ^{[1
]}

GORE, PM ^{[1
]}

HOLMES, DS ^{[1
]}

SAEZ, V ^{[1
]}

WARD, P ^{[1
]}

机构：

[1] GLAXO GRP RES LTD,RES & DEV,DEPT MED CHEM 1,GREENFORD UB6 0HE,MIDDX,ENGLAND

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 13期

关键词：

D O I：

10.1016/0040-4039(95)00250-G

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two different strategies have been developed in order to synthesise an analogue and potential mimic of sialyl Lewis X that incorporates a carboxymethyl group and a C-2-symmetric 2,3-butanediol unit as replacements for the sialic acid and the N-acetylglucosamine residues respectively.

引用

页码：2339 / 2342

页数：4

共 16 条

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