ENANTIOSELECTIVE HETERO-DIELS-ALDER REACTION WITH GLYOXYLATE CATALYZED BY CHIRAL TITANIUM COMPLEX - ASYMMETRIC-SYNTHESIS OF THE LACTONE PORTION OF MEVINOLIN AND COMPACTIN

被引：91

作者：

TERADA, M ^{[1
]}

MIKAMI, K ^{[1
]}

NAKAI, T ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,DEPT CHEM TECHNOL,MEGURO KU,TOKYO 152,JAPAN

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(00)92124-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Asymmetric Diels-Alder reaction with methyl glyoxylate catalyzed by the chiral titanium complex 1 provides the dihydropyran carboxylate in high enantiomeric purity, which can be converted to the lactone portion of mevinolin or compactin.

引用

页码：935 / 938

页数：4

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