MEPHENYTOIN STEREOSELECTIVE ELIMINATION IN THE RAT .2. COMPARISON OF MEPHENYTOIN STEREOSELECTIVE CLEARANCE DURING CHRONIC INTRAVENOUS AND HEPATIC PORTAL-VEIN ADMINISTRATION

被引：3

作者：

AKRAWI, SH

WEDLUND, PJ

机构：

[1] UNIV KENTUCKY,COLL PHARM,LEXINGTON,KY 40536

[2] UNIV BAGHDAD,COLL PHARM,BAGHDAD,IRAQ

来源：

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS | 1989年 / 14卷 / 04期

关键词：

D O I：

10.1007/BF03190110

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：269 / 278

页数：10

共 40 条

[1] MODELS OF HEPATIC DRUG CLEARANCE - DISCRIMINATION BETWEEN THE WELL STIRRED AND PARALLEL-TUBE MODELS [J].

AHMAD, AB ;

BENNETT, PN ;

ROWLAND, M .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1983, 35 (04) :219-224

[2] A PROBLEM WITH QUANTITATION OF MEPHENYTOIN ENANTIOMERS DUE TO CHIRAL INTERFERENCE FROM ITS N-DEMETHYLATED METABOLITE [J].

AKRAWI, SH ;

WEDLUND, PJ .

JOURNAL OF CHROMATOGRAPHY, 1986, 381 (01) :198-200

[3] METHOD FOR CHRONIC PORTAL-VEIN INFUSION IN UNRESTRAINED RATS [J].

AKRAWI, SH ;

WEDLUND, PJ .

JOURNAL OF PHARMACOLOGICAL METHODS, 1987, 17 (01) :67-74

[4]

AKRAWI SH, 1989, EUR J DRUG METAB PH, V14, P201

[5] STEREOCHEMISTRY, A BASIS FOR SOPHISTICATED NONSENSE IN PHARMACOKINETICS AND CLINICAL-PHARMACOLOGY [J].

ARIENS, EJ .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 26 (06) :663-668

[6]

CALDWELL J, 1988, XENOBIOTICA, V18, P59

[7] INVIVO ASSESSMENT OF EXTRA-HEPATIC CONJUGATIVE METABOLISM IN 1ST PASS EFFECTS USING THE MODEL-COMPOUND PHENOL [J].

CASSIDY, MK ;

HOUSTON, JB .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1980, 32 (01) :57-59

[8] AGE-ASSOCIATED STEREOSELECTIVE ALTERATIONS IN HEXOBARBITAL METABOLISM [J].

CHANDLER, MHH ;

SCOTT, SR ;

BLOUIN, RA .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1988, 43 (04) :436-441

[9] CHARACTERIZATION OF ANTIPYRINE AUTOINDUCTION IN THE RAT UTILIZING A NEW MICROSAMPLING TECHNIQUE FOR SERIAL BLOOD-SAMPLE COLLECTIONS [J].

CHANG, SL ;

EMMICK, K ;

WEDLUND, PJ .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1986, 75 (05) :456-458

[10]

COOK CE, 1987, J PHARMACOL EXP THER, V241, P779

← 1 2 3 4 →