AROMATIZATION OF THE B-RING OF 5,7-DIENYL STEROIDS BY THE ELECTROPHILIC RUTHENIUM FRAGMENT [CP-ASTERISK-RU]+

被引：50

作者：

HALCROW, MA

URBANOS, F

CHAUDRET, B

机构：

[1] UNIV PAUL SABATIER, CNRS,CHIM COORDINAT LAB,UP 8241, 205 ROUTE NARBONNE, F-31077 TOULOUSE, FRANCE

[2] INST NATL POLYTECH TOULOUSE, F-31077 TOULOUSE, FRANCE

来源：

ORGANOMETALLICS | 1993年 / 12卷 / 03期

关键词：

D O I：

10.1021/om00027a054

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Reaction of ergosterol or 7-dehydrocholesterol with the ''CP*Ru+'' fragment generated by the protonation of [Cp*Ru(OMe)]2 by CF3SO3H leads to the high-yield selective aromatization of the B-ring of the steroid substrate via a C-C bond-cleavage process, affording near-quantitative yields of the mixed sandwich derivatives [Cp*Ru(eta6-aryl steroid)]+. This reaction has been shown to proceed via an initial C-H bond activation step, yielding a [Cp*Ru(H)(eta5-cyclohexadienyl)]+ intermediate, followed by elimination CH4.

引用

页码：955 / 957

页数：3

共 53 条

[51] SELECTIVE AROMATIZATION OF THE A-RING OF STEROIDS THROUGH DEMETHYLATION BY AN ELECTROPHILIC RUTHENIUM FRAGMENT [J].