机构:
Imperial Canc Res Fund, POB 123, London WC2A 3PX, EnglandImperial Canc Res Fund, POB 123, London WC2A 3PX, England
Treisman, Richard
[1
]
Ammerer, Gustav
论文数: 0引用数: 0
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机构:
Forschungsinst Mol Pathol, IMP, A-1090 Vienna, Austria
Univ Vienna, Inst Algemeine Biochem, A-1090 Vienna, Austria
Univ Vienna, Ludwig Boltzmann Forsch Stelle, A-1090 Vienna, AustriaImperial Canc Res Fund, POB 123, London WC2A 3PX, England
Ammerer, Gustav
[2
,3
,4
]
机构:
[1] Imperial Canc Res Fund, POB 123, London WC2A 3PX, England
[2] Forschungsinst Mol Pathol, IMP, A-1090 Vienna, Austria
[3] Univ Vienna, Inst Algemeine Biochem, A-1090 Vienna, Austria
[4] Univ Vienna, Ludwig Boltzmann Forsch Stelle, A-1090 Vienna, Austria
The mammalian transcription factor SRF (serum-response factor) and the related Saccharomyces cerevisiae transcription factor MCMI are the prototypes of a new class of dimeric DNA-binding proteins. Their function is regulated in part by the interactions of their DNA-binding domains with accessory proteins. Recent work has advanced the functional characterization of the contributions of SRF and MCMI, and their accessory proteins to transcriptional activation.