THE HUMAN PANCREATIC LIPASE-ENCODING GENE - STRUCTURE AND CONSERVATION OF AN ALU SEQUENCE IN THE LIPASE GENE FAMILY

被引:26
作者
SIMS, HF [1 ]
JENNENS, ML [1 ]
LOWE, ME [1 ]
机构
[1] WASHINGTON UNIV, SCH MED, DEPT PEDIAT, ST LOUIS, MO 63110 USA
关键词
RECOMBINANT DNA; NUCLEOTIDE SEQUENCING; TRIGLYCERIDES; PHYLOGENY; CANINE; FLANKING SEQUENCES; INTRONS; PSEUDOGENE;
D O I
10.1016/0378-1119(93)90307-O
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The isolation and characterization of the human gene (hPL) encoding pancreatic lipase is reported. The gene has 13 exons dispersed in about 20 kb of genomic DNA. A pseudogene of hPL was also partially characterized. An Alu sequence is conserved in the homologous introns of hPL and the lipoprotein lipase-encoding gene.
引用
收藏
页码:281 / 285
页数:5
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